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The gene networks present in the platelets and red blood cells are thus expected to be more similar; microarray data from red blood cells should reflect the topology of a platelet's network to a greater extent than that of a lymphoblast network.
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And although it has been reported that DXV activates the Toll pathway [13] and sigma-virus activates the IMD pathway [20], our results are more similar to with microarray analyses of DCV that found no evidence for the Toll or IMD pathways being activated [11].
The transcriptomes obtained using method M were slightly more similar to the microarrays than the data obtained using method C (0.77 ± 0.04 vs. 0.73 ± 0.04).
Multiplex PCR yielded results that most of patients with negative cytology were positive for pathogens that cause STIs, and were more similar to that of DNA microarray, than that of hybrid capture 2 in terms of analytical sensitivity and prediction value of HPV infection.
NGS data were more similar to qPCR data than microarrays.
When fold changes were small (< 2) the microarray and qRT-PCR results were more similar than when fold changes were larger.
Methylation microarray (GEO Series accession number GSE25538) revealed that epigenetically, phESC and hESC were more similar to each other than they were to cell line and tissue samples, but they were not indistinguishable (Fig. 2b).
In contrast, our metaanalysis of exon microarray data with published data sets revealed that RMS samples had an expression profile more similar to neuronal cells and patients than mesenchymal stem cells.
This was not seen as evident with TXNRD1_v2 overexpressing cells, which have a phenotype more similar to control cells and clusters more with these cells than with TXNRD1_v1 overexpressing cells in the microarray analysis (Supplementary Figure S2).
Significantly, the results from our microarray hierarchical analysis study indicate that the genes involved in the pathogenesis of different types of craniosynostosis are more similar than may previously have been thought.
They're more similar than you think.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com