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There was a negative correlation between tissue specificity and the M F ratio, showing that narrowly expressed genes had more similar expression levels in the two sexes than ubiquitously expressed genes (P < 0.01 for all tissues except lung and embryo, F-test corrected for confounding effects by expression level; slope estimate β = −0.38 [brain] to −0.99 [liver]).
In addition, promoters that have similar repetitive DNA profiles regulate genes that have more similar expression patterns and encode proteins with more similar functions than promoters that differ with respect to their repetitive DNA.
It influences the modification of chromatin structure and improves the expression of important genes in development and imprinting, rendering a more similar expression profile to IVF ones.
A smaller distance means that two genes or clusters have more similar expression levels in the tissues analyzed.
This suggests that phylogenetic and/or growth form relatedness demand more similar expression profiles in the midgut of the caterpillars.
Clustering analysis suggests that samples from the same developmental time point show more similar expression profiles than samples from different time points from the same genotype.
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and eight more similar expressions involving,, and for all, where and denote the closed quadrants and and denote the modified radial metrics defined in Definition 6.1.
Our gene expression analysis also showed that 2,4DNT and 2,6DNT share more similar gene expression pattern than the other compounds.
Tone et al. [11] found that gene expression profiles of fallopian tube epithelium from BRCA mutation carriers in the luteal phase were more similar to expression profiles of serous ovarian cancer than fallopian tube epithelium from carriers in the follicular phase.
Interestingly, PYGM mRNA levels were similar in our two patients, in agreement with our previous findings showing more similar PYGM expression levels among related patients as compared to unrelated patients [12].
This indicates two structurally similar compounds are likely to share more similar gene expression profiles in PC3 than in VCAP.
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