More significantly, our studies point directly to an accessible new therapeutic approach to slow Huntington's disease progression, namely, PDE10A inhibition.
More significantly, our study suggests another, potentially more subtle set of reasons to explain differing opinions: experts may hold quite different values, or different versions of the same values.
14, 15 Memory impairment has figured more significantly in some studies than others 9, 10 but is a less prominent feature than in other dementing illnesses.
Even more significantly, these molecular studies of hagfish embryos have demonstrated that, contrary to the suggestions of traditional text-books, the hagfish has de-epithelialized and migrating neural crest cells and vertebral elements [ 19, 30- 33].
In their comparative reviews, both Clark et al. [ 10] and Inglis et al. [ 8] demonstrated that all-cause mortality was more significantly reduced in studies using telemonitoring rather than structured telephone support.
Perhaps more significantly, a remarkable study of the narcissism of celebrities themselves strongly suggests that our role models are far from desirable as people for our children to emulate.
More significantly, a recent study revealed a strong association of WG with an allele encoding class II molecule DPB1*0401 (odds ratio (OR) = 3.91, P = 1.51 × 10-10).
More significantly, a recent study using both cell culture and mouse models demonstrated that oridonin displayed a great antitumor activity specifically in acute myeloid leukemia with the t(8 21) translocation between AML1 and ETO genes.
To identify and determine the predicted non-addictive drugs that were more significantly associated with addiction study than expected, we required that the drugs have a P value of less than 0.05 after Bonferroni multiple testing correction [ 17].
However, this set of DEGs provides a more biologically relevant and powerful AD phenotype compared with previous studies [ 12], since important inflammatory and barrier pathways are more significantly enriched compared to individual studies, as is often observed with meta-analysis derived transcriptomes [ 91].
