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Moreover, this FDR threshold level retained five times more significant transcripts than expected by chance.
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It becomes more significant, when these transcripts showed faithful conservation across thirteen different species suggesting their testicular functions in much broader number of higher eukaryotes.
The enrichment was highly significant in both cases, but more significant in the transcript 3 (P = 3.69 E-19) compared to the transcript 1 transfected cells (P = 1.32 E-14).
Therefore for a given expression level the test becomes more significant for longer transcript lengths.
As pla1-10, the original insertion mutation that suppressed sme2Δ, did not seem to retard vegetative growth, a defect in the polyadenylation complex might have a more significant impact on meiotic transcripts than on mitotic transcripts.
As shown in Table 3, the transcript DHRS9 (ENST00000412271) was more significant than the ANRIL transcript, which is known to be associated with the Chr9p21 region.
Together with further cross generations (15th instead of 4th), this resulted in an almost per gene resolution and more significant associations when the transcripts are used.
However, in contrast to the expression of these PGs, several other pectin degradation-related transcripts presented more significant changes: an increase of three out of four DE PT/PG-annotated transcripts in the S1-S2 trandition andecreaseease of all DE PT/PG-annotated transcripts in the S3-S4 transition.
Using these scores we found that the causative p values of Klf7 on the remaining module transcripts were substantially more significant than the causative p values of Idh1 on those transcripts.
Likewise, genes with a significant treatment, cultivar and time interaction effect had more significant increases in abundance of transcripts related to metabolism than the treatment-significant set as well as for all probe sets on the array.
Although the mixture of TNT and RDX caused an additive impact on reproductive endpoints, expression of the 329 inferred significant transcripts was affected more by TNT than by RDX or the mixture.
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