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Second generation CARs, which are just now entering the clinical arena in the B cell malignancies and other cancers, will provide a more significant test for this approach.
For many experts, a more significant test is whether the law will slow the growth of health costs and provide greater value to consumers, taxpayers and employers in return for the $2.5 trillion a year they spend on health care.
Go Soeda and Vincent Millot should not, and did not, provide any serious resistance, but a more significant test against 26th seed Felicianio Lopez was passed in style.
The more significant test would come when Hyperloop One brings the components together and attempts to accelerate a pod inside a miles-long tube as soon as this winter.
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Stiffer and more significant tests await, including the Concacaf Gold Cup in June and the March friendly with Chile that was announced on Thursday.
More significant tests of Mrs. Whitman's standing with Republican lawmakers will come in the next session, when they will take up hot-button issues like auto insurance, property tax rates and school financing.
But more significant tests lie ahead in amendments to the EU Withdrawal Bill and in particular to the Trade Bill - the latter calls explicitly for the UK to be part of a customs union.
While none of these p-values are significant under a Bonferroni correction, there are more significant tests than would be expected at random – 4 rather than 2 – from 40 trials with a significance threshold of P = 0.05, suggesting that several of the tests are likely to be true positives [21].
In general, larger values of α will result in more significant tests and thus more independent mutations will be inferred, but the number of mutants for a given lethality does not change significantly, which are mostly determined by the percentage of z/z offspring in the F3.
Bicycles are an everyday form of transport for many people, but the principle of human-powered vehicles can also be developed as novelty runabout for tourists or to achieve something much more significant like testing new technology – to break a record, win a prize or cement a reputation.
While high-stakes tests certainly introduce more significant impacts on test takers, the role of classroom assessment should not be ignored in enhancing language learning also (Rahimi et al. 2014).
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