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Here the continued obstacles to doing business are a much more significant hurdle.
While everyone seems confident that the technical challenges of such visions can be overcome, there is perhaps one more significant hurdle to overcome - persuading the general public that a plane without a pilot is safe.
And then, the 73-year-old Seidler explains, there was another, possibly even more significant hurdle: "It was the subject matter.
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Dodelet believes that while his group has "solved the problem" of increasing the activity of the catalyst, two more significant hurdles remain before it can be practical in fuel cells.
The Atlantic Coast Pipeline still faces at least one more significant state hurdle: The Virginia Air Pollution Control Board is set to act next month on an air-quality permit for a compressor station in Buckingham County.
But the industry says focusing on low-cost drugs alone ignores the more significant chronic hurdles to treating diseases of all kinds in developing nations -- lack of public health infrastructure, education, financing and political will.
Paul Armentano, the deputy director of the National Organization for the Reform of Marijuana Laws, said that "removing this arbitrary hurdle to research could have more significant ramifications than simply rescheduling from 1 to 2".
The legal hurdles to sports betting, though, are more significant.
"This is a very significant hurdle overcome and we are delighted but more work is required".
Two months earlier, Glass was far more laid back, saying the proposed rule wouldn't be "a significant hurdle for continuing to grow that business," per Warren's letter.
In Connecticut, the only significant hurdle, Mr. Wollschlager said, was that the program proved more popular than anticipated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com