Principal Component Analysis (PCA) is usually employed as a technique to reduce the number of variables in a data set with a minimal loss of information and to search for a more significant data representation.
Significant data sets are labelled with an asterisk.
For the differential expression tests on the paired tumor-normal miRNA data from our CRC study, the Wilcoxon SRT found many miRNAs which were called significant in the conventional quantile normalized data, even more significant in the data set normalized by the weighted quantile method (Fig. 4).
However, we can see from Fig. 4 that many miRNAs (in the lower right triangle of the plot) that are found significant in the quantile normalized data are found to be even more significant in the data set normalized by the weighted quantile method.
Using data from the School and Staffing Survey (SASS) and a more recent data set, the Teacher Rules, Roles and Rights (TR3), we find that collective bargaining has a significant impact on all aspects of current, qualification-specific salary schedules.
Hence, the National Geographic data set can be seen as a more difficult data set.
For other data sets (Table 4), where more fiber parameters were measured, the number of significant QTLs per data set varied between 11 (Cs8, Lu8 and Mp7) and 23 (Mp8).
This differentiation in the magnitude of concordance improvement, along with the fact that performing trimming leads to a more significant improvement in reads' quality for S2 data set, further indicates that Novoalign is more sensitive towards the changes in sequencing quality.
Previous studies have stated that left sided endometriomas are more common than right [ 13] but there was no statistically significant difference in our data set.
Despite the moderate to high false discovery rate among the SNPs in the discovery data set, more markers were significant (P<0.05) than expected by chance in the validation data set, at least for HTDMYslope, Table 2 and 3.
