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However, this interpretation has been challenged by some archaeologists who argue that the midwinter alignment, where the viewer is outside Stonehenge and sees the sun setting in the henge, is the more significant alignment, and the midsummer alignment may be a coincidence due to local topography.
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For superfamilies which share a close structural relationship but a low overall sequence identity, a two step strategy was used in order to obtain a more significant multisequence alignment.
RScan could get more significant structural alignments on this filtered structural database.
Single_cov2 from TBA package [ 49] was used to filter out the lower-scored alignments in regions with more than one significant alignment.
Probes were eliminated if they had more than one significant alignment (e-value < 0.001) with the reference genome using BLAST analysis (Altschul et al. 1997).
Patients with permanent AF have more significant collagen mal-alignment than those with persistent and paroxysmal AF.
As summarized in Tables 2 and 3, DOMAIN identified more significant non-redundant alignments than NetworkBLAST and MaWISh in both alignments explaining the good scores on the sensitivity metric but also managed to outperform the other methods on the specificity and purity metrics.
A move from RRBS to whole genome bisulfite sequencing (WGBS) has already begun, though these whole genome experiments are much more expensive and still have significant alignment issues.
The lower the E-value, the more significant the score and the alignment.
The lower the E-value, the more significant is the score and alignment between the two proteins.
The analyses of jacking force show that reduction in jacking force is closely related to reduction in friction coefficients, and the effect of lubrication is slightly more significant in the case of curved alignment than the case of linear alignment.
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