In contrast, the Satterthwaite and Kenward-Roger methods can provide tests with very conservative type I error rates when the total cluster number is small (<30) and the conservativeness becomes more severe as variation in cluster sizes increases.
This problem is more severe when examining variation in the release threshold as a parameter value is changed.
The Residual and Containment methods inflate the type I error rates when the cluster number is small (<30) and the inflation becomes more severe as the variation of cluster sizes increases.
The Residual and Containment methods have inflated type I error rates when the cluster number is small (<30) and the inflation becomes more severe with increased variation in cluster sizes.
Long-term climate projections, Dr. Worrall and other scientists say, all point to more curveballs ahead — wider, more severe fluctuations and variations of hot, dry, wet and cold.
According to the UN's World Risk Index, Vanuatu is the world's most at-risk country for natural hazards, due to climate change, in particular more severe cyclones and greater variation between periods of drought and flood.
In the univariate regression analysis, a lower BMI, a history of amputation, more severe foot deformity, more variation in daily step count, and a better perception of footwear aesthetics were significantly associated with higher adherence (Table 2).
Second, they introduce an implicit correlation between size and effect, whereas small structural variations may have more severe effects than some large variations.
While these muscle abnormalities are considerably less severe in younger Mbnl1 KO mice, more severe pathological changes (increased fibre size variation, atrophic and splitting fibres, increased numbers of central nuclei indicative of muscle degeneration/regeneration) were observed in Mbnl1−/−; Mbnl2+/− muscles at 10 16 weeks of age (Fig 2A).
Comparing with the calculated results of the matrices and composite, it can be found that the microstructure variations of matrices are more severe than composite's, which is ascribed to the effect of reinforcements' resistance to the surface layers' deformation.
