Sentence examples for more severe variant from inspiring English sources

To present a detailed clarification of the symptoms at disease onset of Stevens-Johnson syndrome (SJS) and its more severe variant, toxic epidermal necrolysis (TEN), with ocular complications and to clarify the relationship between topical steroid use and visual prognosis.

Our results together with report of Amri et al [ 3] and Pelletier at al [ 11] suggest SBP to be more severe variant with poor prognosis than CNNA.

Some patients develop a more severe variant of sickle cell disease and suffer from additional complications and frequent hospitalizations, while others present with more benign symptoms, or are even asymptomatic.

It has been suggested that bipolar disorder associated with migraine might represent a more severe variant of bipolar disorder, based on an earlier onset of the bipolar disorder and greater social impairment [ 36, 37].

The latter more severe variant named TS2 [27] can be rationalized by the higher expression of exon 8 in the heart and brain (80% versus 20% exon 8A [27]).

The proband carrying both variants shows a more severe form of diabetes compared with the family members carrying only one mutation.

Similarly, 14 cases and 13 controls carried an innocuous rare splice junction variant and no other potentially more severe rare variant, resulting in an OR of 0.62 (P = 0.25) (Table  3).

Accounting for subjects who carried two rare variants, 10 cases and 10 controls carried a rare silent substitution and no other potentially more severe rare variant, resulting in an OR of 0.95 (P = 0.91).

However, our analysis, based on substitution scores and amino acid property matrices, showed that the severity of cancer somatic mutations lies between that of Mendelian disease-related variants and polymorphic variants; less deleterious than Mendelian disease causing variants but more severe than polymorphic variants.

In general, the more severe, chronic G6PD variants exhibited a 'disrupted' pooling structure of the network.

The more severe and more common variant of SAD, however, is the generalized type.