Sentence examples for more severe underlying from inspiring English sources

But, she said, if someone is dealing with a more severe underlying mental health issue that's impairing their decision-making skills, Kondo's methods probably aren't going to be the answer to their problems.

32 Our finding that concurrent treatment with benzodiazepines and higher dose opioids was associated with increased mortality might be a true adverse effect or reflect more severe underlying disease that requires higher doses to relieve symptoms.

RRT before and after contrast interventions may be considered in patients with more severe underlying renal insufficiency who may not tolerate hydration, may need high contrast volumes or are at risk for contrast-induced cardiac decompensation [ 90, 91].

This might reflect the changing landscape of coronary intervention characterised by more patients with coronary artery disease undergoing treatment by percutaneous revascularisation (e.g. balloon angioplasty and stenting), while surgical revascularisation (CABG) is reserved for patients with more comorbid conditions and more severe underlying disease [ 24].

It could be argued that individuals hospitalised with pH1N1 suffer from more severe underlying medical conditions than community controls with underlying medical conditions.

Patients with more severe underlying illness are more likely to develop thrombocytopenia [ 1, 2, 3, 5, 6, 7], and the severity of underlying illness has an important impact on the outcome of ICU patients with severe thrombocytopenia [ 1, 3, 5, 6, 7].

More importantly, anaemia is frequently associated with severe underlying chronic diseases which may compromise long-term survival.

"We need to find out if the company's accounting practices masked severe underlying financial problems".

The utilization of our well-defined IBS population may have resulted in a biased selection of IBS patient types, perhaps those who had more severe disease with underlying inflammatory/immune dysfunction not detected on colonoscopy or histopathology or those more likely to have a diarrheal component.

Therefore, it is reasonable to speculate that a predominantly Th2-mediated airway eosinophilia is likely responsible for mild and moderate atopic asthma, whereas concomitant activation of both Th2 and Th17 cells can be frequently associated with a mixed eosinophilic/neutrophilic inflammatory phenotype underlying more severe disease.

Dominant negative loss of function is therefore the most likely mechanism underlying the more severe phenotype of R482Q/+ than Fbxw7 +/− mice.