Thermal cracking: It primarily occurs due to stress cycles developed as a result of cyclic thermal loads, although under more severe thermal loads, transformation to martensite can also occur [12].
Therefore, they may precede and thereby facilitate the more severe events associated with malignant transformation, such as mutations in tumor suppressors, activation of proto-oncogenes or genomic instability.
Despite more severe grades of dysplasia being associated with higher transformation rates, cases with mild dysplasia may still progress to cancer, while a significant proportion with severe dysplasia do not transform, irrespective of environmental factors (Barnes et al, 2005; Warnakulasuriya et al, 2008; Mehanna et al, 2009; Ferlay et al, 2010; Liu et al, 2011).
It exhibited the qualities of purification ritual, reversion to a more severe form of capitalism; and in the process a transformation of nanny state into stepmother state.
Dysplastic change is reported to be the best predictor of future malignancy, and the more severe the dysplasia, the greater the likelihood of malignant transformation (Schepman et al, 1998).
Second, we analyzed RA patients with SHS ≥1, characterized by a more severe structural disease at inclusion, because of the logarithmic transformation of SHS necessary to meet the assumption of linear regression analysis.
This result is reassuring, in view of concerns of a possible transformation of the strain into a more severe form (7 ), and is in agreement with the antigenic and genetic homogeneity of the virus since its emergence (21 ).
The growing electricity request and more severe commitments on emissions led to the research of more and more efficient energy transformation processes.
In addition to more severe liver fibrosis and tumorigenesis after DEN plus CCl4 treatment, hepatocyte-specific gankyrin-overexpressing mice (gankyrinhep) exhibited malignant transformation from liver fibrosis to tumors even under single CCl4 administration, whereas wild-type mice merely experienced fibrosis.
More severe or less severe?
