Patients experiencing depressive symptoms during a manic episode represent a more severe population.
Results of these additional cognitive debriefing interviews further support the content validity of the GRCD and demonstrate the relevance of the concepts in a more severe population (i.e., those hospitalized due to RSV infection).
An investigation of the BPI-sf among study participants with more severe, active disease was not within the scope of this study, and therefore the extent to which the results of the current study are generalizable to this more severe population are unknown.
One possible explanation is that habitat degradation or destruction outside the study sites but in the local area has affected grassland, thicket, and woodland more so than old-growth remnant patches, resulting in more severe population declines for species found predominantly in regenerating vegetation types.
We can guess that intensivists were prompt to initiate RRT in patients with oliguria or severe metabolic abnormalities and thereby to select a more severe population.
Our study focused on a more severe population of patients, suffering from severe sepsis and septic shock, with higher mortality and morbidity rates than less severely ill ICU populations [ 42].
The subpopulation requiring RRT in the intensive care unit represents the more severe population, and the need for RRT appears to be an independent risk factor for death [ 4].
Results from Fu's F and Tajima's D tests, analyses of mismatch distributions, and comparison of h and π values all suggest rapid expansion after a population bottleneck, with populations in clade A from Africa, Madagascar, the Palaearctic, and the Philippines resulting from a more severe population constriction than populations in grade B from Sundaland, Wallacea, and Australia.
d In the absence of efficacy data for mirtazapine in patients with more severe illness, mirtazapine rates were calculated by applying the mean differences between the less severe and the more severe population to the mirtazapine rates reported in the meta-analysis for the patient population with HAMD-17 ≥ 18. e Germany, Italy, Netherlands, Poland, Spain, Sweden, Switzerland, UK, US, Venezuela.
We tested the hypothesis that species with current ranges that overlap areas previously covered by ice sheets or other extreme environments (such as extreme deserts) might show more severe population reductions as compared to species occurring in less variable conditions [ 2, 3].
