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This finding is likely due to the lower demand in older patients, who may cope better with instability, or indeed may be affected by a more severe pattern of arthritis, with stiffness and osteophytes contributing to stability [4].
For two of the four measures, the Group IIb cases had a more severe pattern than the Group IIa cases, suggesting that the deleterious influence of a high pEGFR expression in the tumours is further augmented by a high CB1 expression.
Further, for many patients it appears to be effective in significantly reducing levels of depression, even in those who start with a more severe pattern including suicidal depression.
However, Dmd mdx/Large myd mice presented a more severe pattern of degeneration at the ages of 21 and 180 days.
We hypothesized that PD-MCI would be characterized by significantly reduced cortical thickness at baseline and develop a more severe pattern of cortical thinning compared to PD-NC and healthy controls over time.
Present findings indicated that CD-low-CU children were inferior in cognitive perspective-taking relative to controls and to CD-high-CU children who display a more severe pattern of antisocial conduct.
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The relationships between individual financial stressors and IPV perpetration were not consistent across patterns of perpetration, although more severe patterns of violence were associated with more of the individual financial stressors.
For example, mutation of Rab23, Fkbp8 or PKA-deficiency affect only caudal spinal cord patterning (45– 47, 110), whereas the Dync2h1/Dnchc2 mutant exhibits a more severe patterning disruption in rostral than caudal regions of the spinal cord (72) and retinoic acid modulates patterning in the rostral spinal cord of quail embryos (125).
The effect of RA on patterning of the regenerate is dose-dependent such that higher levels of ectopic RA for longer periods of time results in more severe patterning phenotypes than lower doses over shorter time periods (Maden, 1983; Tickle et al., 1985).
Male gamblers reported more gambling activity within the last year and showed a more severe gambling pattern.
We have previously reported that HO-1−/− mice exposed to seven weeks of chronic hypoxia develop pulmonary vascular remodeling which is similar to wild-type mice, but their right ventricle (RV) develops a more severe injury pattern characterized by areas of wall fibrosis, apoptosis, lipid peroxidation, and mural thrombi [13].
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more severe profile
more extreme pattern
more severe behavior
more sustainable pattern
more severe fibrosis
more heterogeneous pattern
more severe penalty
more familiar pattern
more severe comorbidity
more severe morbidity
more dangerous pattern
more complicated pattern
more random pattern
more recent pattern
more conspicuous pattern
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