Sentence examples for more severe pathological from inspiring English sources

In contrast, the sham-treated mice and the recipients of iCD8− DC showed much more severe pathological inflammatory reactions.

In contrast, kidneys from transgenic mice showed more severe pathological findings in glomeruli including hypercellularity, mesangial expansion, and glomerulosclerosis (figure 5 and Table 1).

However, the lack of granuloma formation with diffused inflammation observed in the iCD8− DC recipients implies a lack of efficient control for the infection and the development of more severe pathological inflammation.

In contrast, BACE1+/− deletion is no longer sufficient to rescue memory impairments or affect Aβ42 levels in 5XFAD mice as disease progresses into the more severe pathological stage (15 18 months of age) that is accompanied by robust Aβ burden and BACE1 elevation.

In contrast, 129S1/SvImJ mice had delayed transition to decompensated heart failure, with relatively mild alterations in histology and markers of hypertrophy at five weeks post-TAC and preserved systolic function until eight weeks post-TAC, suggesting that 129S1/SvImJ genetic modifiers might protect against the earlier and more severe pathological changes seen in C57BL/6J mice [39].

M. fortis and rats, both of which are resistant hosts to S. japonicum, developed a stronger immune response and more severe pathological lesion in response to the schistosomes than mice during the early phase of the infection; this may be one of the main reasons M. fortis is not permissive to S. japonicum infection.

Ironically the anemia associated with schistosomiasis may actually provide a degree of protection for hosts against the more severe long term pathological consequences of chronic infection.

Most previous reports of HTLV-I bronchio-alveolitis reported more frequent and severe pathological and biological abnormalities of bronchoalveolar lavage fluid in patients with HTLV myelopathy or uveitis compared to HTLV-I carriers without apparent disease [ 6, 8, 14].

In many jurisdictions, however, the term problem gambling is employed to describe all forms of gambling, including the more severe classification of pathological gambling, that lead to adverse consequences for the gambler, others, or the community (Neal et al., 2005).

The observation that such changes influence emotional expression are noteworthy in light of evidence that volumetric reductions in humans with mood disorders are associated with more severe and chronic pathological mood episodes.

Hence, we speculate that there is a spectrum of placental ER stress in vivo, stimulating a mild homeostatic response in the chronically hypoxic placenta at altitude and a more severe response with pathological consequences, in cases of deficient maternal spiral arterial conversion.