Sentence examples for more severe model from inspiring English sources

We can further demonstrate the utility of the adaptive approach in situations of more severe model misspecfication.

Furthermore, the ultrastructural abnormalities in mitochondria as well as intramitochondrial iron deposits were more frequent in the hFXNI154F mutants and a growth defect was only observed in this more severe model.

The lack of SVZ activation in our study could be due to the fact that the Batista study was examining R6/2 animals [5], which represent a more severe model, bearing a closer resemblance to juvenile-onset HD.

We also studied the role of NRG1 in a more severe model of nerve injury: sciatic nerve transection and reanastamosis (Supplementary Fig. 1B).

It would be interesting to repeat our experiment in a more severe model, investigating whether increased cholesterol-associated cartilage damage is detected.

We established a model of resolving peritonitis as well as a more severe model for comparison that progresses to systemic inflammation by injecting 2 distinct quantities of zymosan intraperitoneally into 2 separate groups of mice.

Previously, we have assessed the impact of inhaled CO on a variety of more severe models of pulmonary inflammation/injury than used here [10].

Further studies are also warranted to examine the ability of MAT.Ang-1 to reduce mortality in more severe models of sepsis.

This is crucial to our interpretations, as previous experiments exploiting more severe models of volume-overload hypertrophy document changes to m-CPT1 activity accompanied by preserved mitochondrial function [44].

The AAB model was also chosen over more severe hypertrophy models, such as the transverse aortic constriction (TAC) model, as they can result in a very rapid onset of overt heart failure, which would have limited our ability to examine the metabolic changes that occur during the highly clinically relevant period of compensated hypertrophy.

This is consistent with previous reports describing that elevated IL-17A induced neutrophil recruitment and increased inflammation in a more severe CLP model [7].