Sentence examples for more severe histopathological from inspiring English sources

Moreover, we have found that as serum levels of TTG IgA increase there is a linear tendency toward more severe histopathological lesions and higher γδ IELs counts.

As serum levels of TTG IgA increased, a linear tendency toward higher γδ IELs counts in active CD patients (Spearman ρ = 0.422, P = 0.002) and more severe histopathological lesions (Spearman ρ = 0.393, P = 0.003) were observed.

As a result, H3N2 vaccinated mice had a fatal clinical outcome of infection with IAV IND/05, associated with higher virus titers and more severe histopathological lesions in the lungs seven days p.i. and reduced virus-specific CD8+ T cell responses compared to mice that experienced a productive, self-limiting infection with IAV HK/68.

Fullner et al reported that a hap mutant is more lethal in a pulmonary murine model and caused more severe histopathological damage than its wild-type parent in the lungs of survivors, although no difference was seen in the induction of inflammation [14].

As a result H3N2-vaccinated mice continued to loose body weight after A/H5N1 infection, had 100-fold higher lung virus titers on day 7 post infection and more severe histopathological changes than mice that were not protected by vaccination against A/H3N2 influenza.

Other techniques have been implemented to identify more severe histopathological alterations.

However, this translates into only a slightly more severe FRDA-like behavioural, biochemical and histopathological phenotype for YG8sR mice compared with YG8R and YG22R mice; the YG8sR disease phenotype remains slowly progressive.

The most relevant finding of our study was that in PLPtg mice the histopathological phenotype was much more severe when PD-1 was absent.

With symptom progression, nerve-lesions detected by MR-neurography were also apparent at more distal levels, correlating with the histopathological amyloid detection in more severe cases.

Since dPGS treatment led generally to less severe histopathological OA in the rats, more effective treatment profiles should be selected (earlier start or longer duration of dPGS treatment) in the future.

Consistent with the inflammatory responses, the histopathological damage to lung tissue was more severe in animals with control ventilation than in those with spontaneous breathing.