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Further, migraineurs with EDS experienced a more severe headache, depressive mood, and higher impact of headache.
Cephalea is a chronic and more severe headache, sometimes remitting and commonly refractary to therapy.
Specifically, better coping skills reduced depression among those with more severe headache pain.
Most consistently, higher quantitative demands and role conflict, and lower decision control, control over work intensity, and job satisfaction were related to more severe headache at follow-up.
Therefore, ILOC played a protective role with regard to depression among those who reported more severe headache pain.
In addition, we found that participants with TTH with RLS had more severe headache intensity than those with TTH without RLS.
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Patients with higher frequencies of clinic visits for headache before the index date might have experienced more severe headaches, which could have precluded their premature termination of treatment.
In fact, sleep deficiency is associated with more severe headaches [39] which would explain why sleep quality, but not depression, also mediated the relationship between the pain interference (i.e., bodily pain domain) and headache frequency.
Although this paradigm may increase the placebo effect, it was selected because headaches in CM are typically reported to be mild or moderate compared with more severe headaches in episodic migraine [14, 15].
Potential predictors for the absence of headache improvement following aneurysm treatment were: having migraine prior to treatment, having more severe headaches prior to treatment, stent-assisted coiling and higher pretreatment trait anxiety.
The first group presented increased frequency of headache-days per month (9.18 vs. 3.13, p<0.001), more severe headaches (8.1 vs. 6.7, VAS, p<0.05), more expressed anxiety and depression, according to Spilberger test (36.5±1.7 vs. 29.26±1.7, p<0.05) and depression Beck score (8.03±0.09 vs. 5.01±0.6, p<0.05), respectively.
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