Sentence examples for more severe experimental from inspiring English sources

Macrophage activation associated with chronic murine cytomegalovirus infection results in more severe experimental choroidal neovascularization.

In addition, deletion of the autophagy gene ATG16L1 in mice resulted in inflammasome activation and more severe experimental colitis [22].

With regard to neurological disorders, mice lacking H3R (H3R−/−) develop more severe experimental allergic encephalomyelitis (EAE) with a marked increase of blood brain barrier permeability and an increased expression of macrophage-inflammatory protein (MIP -2 and interferon-inducible protein-10 (IP-10/CXCL10) on peripheral T cells.

These mice have been found to develop a more severe experimental encephalomyelitis [ 45], a disease model that is induced by immunization against nervous system-derived antigens, which have little to do with arthritis.

CB2 receptor KO mice develop a more severe form of experimental allergic encephalomyelitis in comparison with WT mice, which is a consequence of increased T-cell activation and decreased T-cell apoptosis in KO vs. WT mice [53].

By contrast, Morris et al. found that mice with pan-pancreatic β-catenin deletion, driven by Ptf1a Cre, exhibit a more severe response to experimental pancreatitis, including sustained loss of acinar cells (Morris et al., 2010).

In vivo antibody-mediated blockade of B7-H3 in mice has been reported to enhance T-cell activation and to lead to more severe forms of experimental autoimmune encephalitis (Suh et al, 2003; Prasad et al, 2004).

The additional LPS exposure reflects a more severe form of experimental asthma, as it enhances the number of cells in bronchoalveolar lavage (BAL) and increases neutrophil recruitment, whereas the number of eosinophils have been reported to be both increased [ 2] and reduced [ 3].

Vitamin A deficiency is associated with a decreased small bowel villus height and a reduced disaccharides activity leading to more severe intestinal injury in experimental enteritis [ 95].

Given the profound vascular effects subsequently reported in the hippocampi of pilocarpine- and kainate-treated rats [8], prolonged SE may be an insult more severe than that observed in other experimental epilepsy models, or in humans who exhibit a highly selective and relatively limited pattern of neuron loss [2].

Clinical symptoms in ducks of the control group seemed to be more severe that has previously been reported for experimental inoculation of naive mallards with HPAIV H5N1 [23] [23].