The integrity of ERP component structure was poorer, with more severe EEG background abnormality and fewer ERP components being isolated.
It is worth mentioning that for all images and the two domains, the WSQ compression does not affect significantly the ridges; the visual alterations are more severe in the background especially around the ridges area.
In addition, there was a clear gradation from milder to more severe epileptiform and background EEG abnormalities in patients with the later clinical stages of the disease.
The proposed clinical stages are associated with worsening cortical and cerebellar atrophy on brain imaging and more severe epileptiform and background EEG changes.
If Glc7 directly opposes Ipl1 to dephosphorylate substrates involved in chromosome segregation, then we would expect that some traits associated with the GLC7 mutations would be more severe in an IPL1 background than in the ipl1 -2 background.
Interestingly, the effect of p53 loss on embryo implantation is more severe in C57BL/6 J background, while the effect on spermatogenesis is more obvious in 129Sv background, suggesting that the genetic background of the host can influence the effect of p53 loss on implantation [ 18].
In addition, expressivity of the hearing loss phenotype varies with genetic background; it is more severe on the 129S6 and C57BL/6 backgrounds than on the CBA/Ca and BALB/c backgrounds.
The phenotype of Fn1-null embryos varies depending on the genetic background; it is more severe on 129S4 than on C57BL/6J background (George et al., 1997).
The principal weather events we need to plan for are more rainfall over sustained periods in winters, more intense localised rain storms particularly in the summer, albeit summers on average will be drier and hotter overall with higher peak temperatures, and more severe storms, against a background of rising sea levels.
