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If there are more sequences than expected belonging to a particular chromosome, then the fetus probably carries an extra copy.
If S>S1+S2, then the split project has assembled more sequences than the original project.
That is, at a false discovery rate of 5%, SAM identified more sequences than our proposed method in the WT model, and we identified more sequences than SAM in the PXR-KO model.
In the case of one library that contained two initially-biased sequences, bareback-processing recovered four- to eight-fold more sequences than 'image-flags' (Fig. S1d-f).
The new standard pipeline analysis was able to recover more sequences than the previous version, however recovery was generally poor (Fig. S2).
The UP clusters are longer and contain more sequences than the SO clusters (see above).
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This is more than an order of magnitude more sequence than is lost from other taxa.
We also note that our phylogenetic analysis is based on more than 40 times more sequence data than previous analyses.
FASTF requires about 25% more sequence data than FASTS for equivalent sensitivity, but additional sequence data are usually available from mixed Edman experiments.
Although cell cycle control is an ancient, conserved, and essential process, some core animal and fungal cell cycle regulators share no more sequence identity than non-homologous proteins.
Secondly, 454 sequencing can generate more sequence data than the Sanger sequencing.
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