Sentence examples for more sequence variants from inspiring English sources

Such a library would correctly identify more sequence variants than a traditional tiling library with variation at the single position where multiple mutations occur frequently within single probes and those mutations reflect a limited set of possible variants.

Each PCR primer pair combination amplifies one or more sequence variants.

Intergenic/non-transcribed regions by comparison typically contain a much higher proportion of unpaired, broken reads and more sequence variants.

Lack of a geographic structure in the gdh and ITS genes contrasts the fact that more polymorphic sites and ultimately much more sequence variants were available for these genes compared to gtf.

First, the association can be a result of two or more sequence variants in the region that individually do not confer a detectably increased risk for prostate cancer, but when using the haplotype-association strategy the impact of the combined risk becomes statistically significant.

More than 30 sequence variants of the FMO3 gene have been reported to cause trimethylaminuria.

To date more than 1600 sequence variants of BRCA1 and 1800 sequence variants of BRCA2 have been described [ 14].

However, an important proportion of HCM patients, 5 7% of patients in our experience (using Sanger Sequencing), has been reported to carry multiple (2 or more rarely 3) sequence variants in sarcomere genes.

Mutations in the POLG gene, encoding the catalytic subunit of the human polymerase gamma, have been linked to a wide variety of mitochondrial disorders that show remarkable heterogeneity, with more than 200 sequence variants, often very rare, found in patients.

The interpretation of SNP data in Atlantic salmon is complicated by the WGD, which has made it difficult to differentiate between single locus SNPs and the more complex paralogous sequence variants (PSVs) and multisite variants (MSVs), which arise from gene duplicates [ 16, 17].

62, 63 More than 300 unique sequence variants have been identified in this gene, including more than 80 pathogenic mutations (http://www.lovd.nl/mutyh).nl/mutyh