Tebbetts says that more specific antibodies are made using "peptides from the more sequence-diverse areas of N- and C-terminal regions [of GPCRs], or the third intracellular loop combined with carrier proteins as immunogens.
However, replacing missing residues with XXs does not work with large numbers of MVP sequences, or for more diverse sequences such as for invertebrates, as there are gaps in the ASR due to sequence divergence, rather than there being a single sequence region missing.
In general, spacer sequences are more diverse than rDNA sequences because of a low functional constraint.
Two years ago, a British research group found that a more diverse sequence of seven nucleotides could also form a foursome.
Furthermore, antaRNA produces more diverse sequence sets compared with RNAiFold, which shows a trend to non-diverse subsequences.
In contrast, LPMO1 enzymes are present in a polyphyletic clade, indicating a more diverse sequence space and potentially varied enzyme function.
In addition to the highly enriched miRNA sequences, there were also lowly expressed but much more diverse sequences of other ncRNAs, such as rRNAs, tRNAs, mRNAs, snoRNAs and other sRNAs in the Rfam database.
Accordingly, the fact that the B genome sequences were more diverse is not an artifact from the use of more than one representative accession.
These reconstruction tests suggest that ANSCESCON may be a better tool to reconstruct ancestral sequences compared to PAML, PHYLIP and PAUP* if the given alignment contains more diverse sequences.
Designed sequences can be more diverse than natural sequences, possibly avoiding some limitations of experimental databases.
Yet, we also found seven additional ICK motif containing sequences, which were more diverse in length, signal sequence and cysteine arrangement, suggesting the recruitment of multiple ICK motif encoding proteins for black widow venom expression.
