The transcript abundance of certain genes in the mosquito carcass could reflect an averaging of gene expression levels across a variety of tissues and organs and therefore result in a lack of difference between the compared samples, whereas the cell line is likely a more homogenous, simpler and more sensitive system.
The use of the stably transfected cell line allowed us to bypass the effects of our experimental manipulation on the transcription of endogenous progranulin and focus on the effects of miRNAs on posttranscriptional regulation of progranulin expression with a more sensitive system.
Therefore, this model of demyelination may provide a more sensitive system in which to study the effectiveness of neuroprotective drugs.
In monitoring healthcare outcomes, a more sensitive system, i.e. one with shorter OC-ARL is to be preferred.
Monocytes also express FcγRI, FcγRIIa, FcγRIIb and, sometimes, FcγRIIIa 12 and their activation by Ab-coated platelets is a more sensitive system as it is partially mediated by the interaction between platelet P-selectin and P-selectin glycoprotein ligand-1 on monocytes 11.
Use of this more sensitive system increases the ability to detect trends in TSS, which may develop because of changes in bacterial virulence characteristics, host characteristics such as the use of new devices or products, changes in human behavior, or changes in host susceptibility.
Moreover, in the last few years, improvement in the surveillance for rabies and several other less-studied infectious diseases by the Brazilian Ministry of Health and Secretary of Health for Pará State has resulted in a more sensitive system for detecting and investigating all relevant and unusual episodes suspected to be bat-transmitted rabies.
The new equipment, including smarter bombs, more sensitive surveillance systems and more sophisticated communications networks, is not in plentiful supply.
Trifiletti explained that it might be their more sensitive endocrine systems.
