These specific factors may also help in identifying the patients, who are more sensitive to FOLFOX regimen.
This explains the potency of this regimen in NSCLC, but clearly resistant patients exist, and indeed some tumors in this study were more sensitive to alternative regimens.
Furthermore, some studies have identified NLR as a valid tool to identify patients who are more sensitive to specific chemotherapy regimen both in the surgical and nonsurgical setting [ 5, 16, 28, 33, 35, 45, 55].
A number of studies in ovarian tumors, support the hypothesis that inherited genetic defects in BRCA1/BRCA2 render these neoplasms more sensitive to platinum-based regimens.
Correct dosing reflects the percentage of days on which the medication is taken as prescribed and is therefore much more sensitive for deviations from the prescribed regimen than taking compliance data.
We also confirmed that HCC patients with high tumor PCAF expression had better postsurgical prognosis and were potentially more sensitive to 5-FU-based chemotherapy regimens.
Targeting of Mcl-1 via RNA interference is a potential therapeutic strategy to render HCC cells more sensitive to chemotherapy and molecularly targeted treatment regimens.
New studies, with more sensitive methods and larger number, focused on the effect of these regimens on renal function of HIV infected children are warranted.
As at May 2014, 4094 antiretroviral naive patients in the SHCS started treatment with a cART regimen and recorded a first episode of viral suppression using more sensitive assays; 1672 of these patients later recorded a subsequent episode of viral suppression on cART using more sensitive assays.
Many of these treatments leave the skin more sensitive to ultraviolet light and must be followed up with a strict sun protection regimen.
