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Recently, 99mTc-labelled lactadherin was introduced as a more sensitive protein for the detection of PS because of a higher affinity [12 15].
One technology that promises to yield more sensitive protein maps has been used for the quantitative mass spectrometry of small molecule analytes for years.
Using more sensitive protein detection methods, such as the differential in-gel electrophoresis (DIGE) technique and analyzing two different brain regions at two different age stages, 87 quantitatively variant proteins were detected in the parkin knock-out mouse [5].
These will include a more sensitive protein measurement technique and several cell lines differing in tumorigenicity/invasiveness.
This approach may be generally applicable to a wider range of drugs, including more sensitive protein and oligonucleotide therapeutics.
This screen involved the use of a more sensitive protein stain (acid violet) for improved detection of paraproteins.
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To further increase the function assignment of the mRNA reads, the more sensitive protein-sequence alignment was qualitatively evaluated using BLASTX [ 19, 34].
rDNA has been suggested to be more prone to damage than other DNA regions and the protein-dense nucleolus has been shown to be more sensitive to protein damage during cellular senescence (Kobayashi 2008).
Moreover, antigen detection by Western blotting is more sensitive than protein detection by silver staining.
In several studies specific subgroup analyses were conducted to identify subgroups whose BP is more sensitive for protein intake.
These methods are more sensitive than protein truncation testing, but may still not detect all mutations.
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