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In all cases, longer sequence reads resulted in more sensitive assignment of annotations to the DNA sequences, as seen before (Wommack et al., 2008).
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Being mapping-based it is more sensitive than assembly-based allele assignment for short read data sets, and can be run locally without reliance on web-based services or data uploads.
With the growing disparity between the number of available protein sequences and number of experimentally determined structures and functions, we are reliant on more sensitive and effective computational methods for domain assignments.
The metric is then used to explore which estimators are more sensitive to misspecification of the outcome and/or treatment assignment model.
To further increase the function assignment of the mRNA reads, the more sensitive protein-sequence alignment was qualitatively evaluated using BLASTX [ 19, 34].
Because of its ability to incorporate haplotype assignment uncertainty, the REG test should be more sensitive than the LOCAL test, and the results of Table 3 seem to confirm this.
Our framework can be used as a checklist to assess which capacity phenomena are considered in an assignment model and to inspire the development of more sensitive models.
While the assignments to headwater populations (Iešjohka and Kárášjohka) were relatively invariable, the assignments to the two mainstem populations were more sensitive to the number of K in the analysis.
Compared to general domain annotation servers such as PFAM, daTAA captures more domains and provides more sensitive domain detection, as well as integrated and detailed coiled-coil assignments.
RNA-Seq has obvious advantages over existing methodologies such as enabling large-scale functional assignments of genes, more thorough qualitative and quantitative analysis of gene expression, more sensitive and accurate profiling of the eukaryotic transcriptome including non-model organisms [ 42– 42].
The match task can be viewed as a more sensitive measure of how well people decode the color-coding system because participants are explicitly asked to solve an assignment problem.
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