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Moreover, in this study, disc height has been assessed quantitatively and treated as a continuous variable, providing a more sensitive assessment than previous methods that have employed qualitative descriptors such as 'normal to slightly decreased' intervertebral disc height as a measure of disc degeneration [ 20].
The myocardial performance index (MPI), a parameter derived from echocardiographic tissue Doppler measurements, allows for a more sensitive assessment of global cardiac function than do traditional metrics for cardiac function.
A more sensitive assessment of proliferation involved labeling cellular proteins with the fluorescent molecule, CFSE [49].
The mPT assay was a more sensitive assessment of apixaban activity than INR or aPTT.
This affords a more sensitive assessment of synchronization than the direct correlation between the discharges of pairs of neurons.
The grading systems used by other guidelines did not allow for this more sensitive assessment of the evidence.
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Future studies may benefit from more sensitive assessments in evaluating proposed mediators of change.
Recently, more sensitive assessments of microbicide-induced inflammation have been described employing measurement of soluble cytokines [ 8], and by immunohistochemical staining of tissue inflammatory markers [ 9].
More sensitive assessments of pleural abnormalities can be done with computed tomography (CT) scans; however, cost, potentially unnecessary exposure to ionizing radiation, and risk of frequent false-positive findings reduce the utility of CT scans for screening low-risk individuals.
Perhaps more sensitive capacity assessment tools, such as the MacArthur Competence Assessment Tool--Treatment (MacCAT-T) should be evaluated for use in this setting [ 56, 58].
By subjecting all included patients to further review and applying the above described method, a more sensitive ADE assessment by the experts is expected.
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