Sentence examples for more sensitive alignment from inspiring English sources

Seed-and-extend methods break reads into seeds which are mapped to the genome, and much like seed-based unspliced aligners, candidate mapping locations are examined with more sensitive alignment methods.

More sensitive alignment methods are then used to eliminate candidate regions where seeds cannot be extended to full read alignments.

However, it should be noted that all methods have adjustable alignment parameters, and in most cases could be optimized for more sensitive alignment.

(The developers of SSAHA have implemented a new version, SSAHA2 [ 22], which combines the original SSAHA searching algorithm with a more sensitive alignment program.

BWA can be run in the more sensitive alignment mode 'bwasw' that employs Smith Waterman style alignments for increased accuracy, but we found it too slow for a whole genome scale.

Our results on simulated data let us expect an even higher performance for more sensitive alignments and appropriate multi-mapper handling.

As the state of indels is much more sensitive to alignment problems, we used a more stringent qualification procedure for these.

Furthermore, there is currently no evidence that phylogenetic trees inferred from ITS are more sensitive to alignment conditions in Microbotryaceae than in other groups of comparable rank, because these effects have rarely been investigated.

The more sensitive multiple alignments failed to record any human-rodent syntenic regions involving the SULT1A1, SULT1A2, or SULT1A4 loci but detected synteny involving the SULT1A3 loci and both rodent genomes.

Novoalign was chosen instead the BWA mapper used in the original study, as it is implements a more sensitive and accurate alignment algorithm that also allows for the usage of an ambiguous reference allowing the alignment of more reads with greater specificity.

LASTZ was chosen because it was shown to be more sensitive in the alignment of intergenic sequences.