Sentence examples for more selective drug from inspiring English sources

The aim of this approach is the production of a more potent and/or more selective drug compared to the single entity.

Unfortunately, such promiscuous use of drugs is the best way to put selection pressure on the worms and encourage the evolution of resistant strains.What is needed, says Dr Kaplan, is more selective drug use, and better management.

It became clear that α1- and β-adrenergic receptors did not share stringent homology in the ligand-binding pocket but this difference has allowed for more selective drug design.

Such work could also lay the foundations for more selective drug targeting in disease therapy.

These results suggest that L1-regularized methods provide us with more selective drug substructures and protein domains, without losing important information encoding protein ligand interactions.

Hence, the understanding of MMP-2's mechanism of action (paracrine versus autocrine) and determination of the cellular source/targets of MMP-2 are crucial in the development of novel and more selective drug design.

They have been replaced by more selective drugs.

"We hope by knowing the three-dimensional structure we might be able to develop more selective drugs and more effective drugs," Dr. Kobilka said.

More recently, research has focused on identifying the intracellular effectors of these signaling cascades in the hope that more selective drugs may be rationally designed for therapeutic intervention.

Decades of research and pharmaceutical development have yielded the safer, more selective drugs used today; however, these modern drugs appear to act through the same fundamental mechanism of neurotransmitter modulation.

Allosteric sites are less structurally conserved than their corresponding orthosteric site and thus provide new opportunities for the development of more selective drugs.