CD11b+ cells showed a more round-shaped morphology in pMCAo and TBI, in line with increased infiltration of peripheral immune cells.
Moreover, miR-21 overexpressing cells adopt a more round cell-shape morphology.
Inhibitory anti-kif2a antibodies added to spindle assembly reactions had no effect on steady-state spindle morphology or size in stage 3 extracts, but caused a dramatic increase in spindle size and change in spindle morphology to a more round lantern shape in stage 8 extracts.
Treatment with MLI affected breast cancer cell morphology, being associated with a more round form, smaller size, formation of cell-aggregates and detachment from the surface (data not shown).
Structural and cellular changes include increased collagen fiber disorganization, hypercellularity and a change in cell morphology from elongated spindle-shaped cells to more round, plump cells.
Contrary to the previous organelles which display predominantly a round morphology, the mitochondria exhibit a filamentous shape and are consequently more challenging to track.
We also noted that a high proportion of vehicle-treated wound macrophages exhibited a round morphology, whereas C15-treated wound macrophages had many protrusions, which may reflect a more migratory or phagocytic phenotype.
Lymph node involvement can be suspected if there is lymph node enlargement (more than 1 cm in short axis diameter, or if there are suspicious features such as round morphology or central necrosis, which have a high specificity for metastases).
Several natural products were found to alter S. pombe's morphology relative to control, in terms of elongating cells, shrinking them, or making them more round.
All cells selected initially had a round morphology.
