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Thus, more robust trials are needed to build evidence about these interventions.
More robust trials are needed to confirm these findings, using objective measures of health-related behavior in larger samples.
However, much of the evidence derives from relatively small, retrospective and/or single-centre studies and requires confirmation in more robust trials.
Far larger, more robust trials are now required that not only monitor serum 25(OH D concentrations but also explore much further the potential mechanism behind this apparent discrepancy in effectiveness between the 2 forms of vitamin D available.
Tabulation of the more robust trials revealed that interventions that significantly improved adherence contained more components considered important by patients than interventions where no statistically significant effect was found.
Notwithstanding the difficulties underlying the execution of this type of complex clinical trials, larger and methodologically more robust trials are very much needed to confirm the findings of the present review, and to further identify characteristics of successful programs.
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The use of multiple operators to measure repeatability provided a more robust trial compared to previous studies that involved only single operators [28], [29], [30].
Nevertheless, with greater resources, a more robust trial design could have been adopted.
Using repeated, independent trials of a BW treatment system provides a more robust test of performance than a single trial for multiple reasons.
More robust clinical trials are needed to corroborate these findings.
The setting up of such studies, using a fully integrated approach that incorporates network biology, where sampling occurs after the administration of causative factors will help us better understand the disease and design more robust clinical trials.
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more robust tests
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