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Put together, this review was limited to a narrative synthesis of evidence rather than a more robust quantitative meta-analysis.
Responsiveness statistics: Several methods have been proposed to provide more robust quantitative expressions of the magnitude and meaning of changes in instrument scores.
Univariate analysis is limited by factor interactions and confounding variables; therefore, multiple linear regression was employed to build a more robust quantitative model.
NMR offers advantages through milder sample processing and a more robust quantitative output, but MS-based methods have dominated the field due to their superior mass resolution, sensitivity (atto- to zemptomolar 86), and mass accuracy (sub millidalton 87).
The application of more robust quantitative proteomic approaches, such as difference gel electrophoresis (DIGE) or MS-based stable isotopic labeling, should lead to a better coverage and accuracy of protein changes.
The inclusion of the Expanded Discovery Set-1 was justified in these later evaluation steps since the more robust quantitative measure of MF peak area was used with the Agilent Quantitative Analysis software.
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However, when quantifying compounds as produced by metabolic processes, especially when those compounds are in a complex mixture, the combination of multiple techniques is warranted until a single more robust qualitative and quantitative analytical method is developed.
Ron Burke, a director with the Union of Concerned Scientists, which helped shape the plan, said it was "more robust and quantitative than those in any other city".
For this reason we deliberately chose for the more robust and quantitative donor based methods, i.e. FLIM and acceptor photobleaching, to measure the FRET efficiencies in living cells.
Our data suggest that fluorescence-based amplicon sizing is more robust for quantitative determination of dominant LH variants than direct Sanger sequencing with Big Dye terminators.
DNA methylation studies are more robust and quantitative compared to RNA expression studies and therefore amenable to high throughput analysis or use as clinical biomarkers.
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