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That sequencing technology and more rigorous replication has transformed the study of individual variation and the work of the twin studies group.
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To subject our hypothesis to a more rigorous test, we allowed replication forks to travel greater distances from the origins before HU treatment and then measured the sites of chromosome breakage in samples recovering from HU.
Future studies with more rigorous measurement of infection are needed for replication of these results and to understand potential mechanisms of the observed link.
More refined null expectations and adequate replication are needed to allow more rigorous conclusions.
While those models were evaluated with respect to their ability to predict the wild-type replication profile, they should be instrumental in defining the expected differences in the replication profiles upon S phase perturbations, and thereby interpreting mutant effects in a more rigorous manner.
That's encouraging news to Brian Nosek, a psychologist at the University of Virginia in Charlottesville who led the mass replication effort, which began in 2011 with the goal of putting psychological science on more rigorous experimental footing.
The minimalists were more rigorous.
So was adjusting to more rigorous competition.
There are more rigorous performance standards.
I know which is more rigorous.
The stage is more rigorous.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com