In addition, the use of convex optimization puts existing concepts for surrogate representation on a more rigorous basis and several conclusions are drawn, particularly on the importance of specific CPTs and weighting factors of regression-based approaches.
Obviously, concrete conclusions require more rigorous examination and careful parameterization.
Although rare genetic variants may contribute to disease susceptibility, such conclusions require more rigorous experimental validations as recently exemplified for a dominant-negative STXBP2 variant [ 51].
More rigorous evidence is needed for drawing conclusions.
However, after more than a decade of inquiry, still more rigorous research is needed before definitive conclusions about the nature and usefulness of social capital as a means of HIV prevention can be drawn.
Rebus sic stantibus, it seems hard to establish where does this oral burning really come from (carbidopa/levodopa, PD, anxiety/depression, or a combination of these variables?) This case highlights, for all health care professionals, the need of a more rigorous diagnostic protocol before drawing any conclusion on a possible etiology of any oropharyngeal complaint.
If found to be at an increased risk of breast cancer progression, women who have had a previous hysterectomy may benefit from more rigorous surveillance or targeted therapy In conclusion, serum VEGF appears to be influenced by the presence of a postmenopausal uterus.
Larger and more rigorous studies are needed to enable strong conclusions and clinical recommendations to be made.
Note that, although to two approaches are markedly different, the results were very similar and using this more rigorous approach did not changed the overall conclusions drawn.
The authors suggested the need for more rigorous studies, especially randomised controlled trials, before conclusions could be drawn on the efficacy of mHealth interventions to improve TB medication adherence.
