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Exact(14)
By contrast, XBP1-BSL NZ was predicted to assume only one conformation (Figs 4A and EV4A), locking it into a more rigid conformation that mimics the most stable XBP1-BSL conformer (Fig EV4B).
The more rigid conformation acquired by the calixarene in the complex and the non-symmetrical arrangement of the coordinated nitrates result in a particular feature of the emission spectra at 77 K.
This more rigid conformation of PAHy is related both to the network of hydrogen bonds capable of stabilizing the overall structure and to the lower molecular weight with respect to PHEA.
The R-sulfoxide group forms an intramolecular hydrogen bond with the C-terminal amide, conferring a more rigid conformation with all residues protruding outside except for Leu2, in which the Gla1 and Tyr3 share an overlapping function as previous SAR studies proposed.
In contrast to famitinib, our synthetic compounds possess a more rigid conformation than sunitinib and demonstrated superior inhibitory activity of VEGFR-2 and PDGFRβ to sunitinib.
Cross-linking between C181 and 184 could impose a more rigid conformation and potentially alter H-Ras membrane interactions.
Similar(46)
The reduced viscosity of pseudopolyrotaxanes in aqueous solution has smaller change with the change of the concentration or temperature, which is consistent with the hydrodynamic radius and more rigid chain conformation because of the threaded CB[6].
In Figure 4, both mutant (R326H and R356Q) structures showed an increase in helical content which leads to became more rigid on conformation.
Furthermore, the dramatic blueshift observed for HS-136 bound to the deposits indicates a more twisted and rigid conformation of this dye than of the other LCOs.
The MWapp of the RII tetra-tandemer decreases slightly with an increase in Ca2+ concentration (Table 1), suggesting that the divalent metal cation helps the protein form a more compact and rigid conformation.
Related to the latter observation is a more recent study by Villamil Giraldo et al. showing that Ca2+ in concentrations higher than its average ER concentration causes a switch in the C-terminal structure from disordered peptide to a more rigid and compact conformation.
More suggestions(15)
more twisted conformation
more compacted conformation
more active conformation
more rigid security
more rigid footballing
more symmetric conformation
more inactive conformation
more stable conformation
more functional conformation
more rigid work
more authentic conformation
more rigid body
more coily conformation
more crumpled conformation
more open conformation
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