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These discrepancies resulted from journal articles' (1) omission of complete SAE data, (2) reporting acute phase study results only and (3) more restrictive reporting criteria.
Importantly, while some journal articles appeared to apply more restrictive reporting criteria that might lead to omitting certain data, the many articles that did report exact SAE numbers often did so regardless of presumed causality to the study drug.
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Our finding that new statin use levelled off starting in the late 2000s may be due to statin treatment saturation within a large pool of previously untreated individuals, or possibly more restrictive use after reports of potential adverse long-term effects of statins.
But now the British, after some remarks about privacy by the top legal man in their new government, are nervously pondering European ways of combining press freedom with a more restrictive attitude to the reporting of the private foibles (and physiques) even of public figures.
For instance; parents who were concerned about their child being or becoming overweight reported more restrictive feeding practices of both types, whereas parents who were concerned about their child being or becoming underweight reported more pressure to eat.
Additionally, any online communication from a government-affiliated entity was included as a formal source report in MoH+, and a more restrictive definition of formal source reports could have been used.
In other specialties, where patient integrity is more easily violated, such as obstetrics/gynecology, patients have repeatedly reported a more restrictive attitude towards student participation [ 8, 24].
Some have argued that another measure related to the modulation of the RF signal should be used to set a more restrictive standard for example, the BioInitiative Report (BioInitiative Working Group 2007).
This new rule is, of course, more restrictive and excludes all individuals who report only one of the three entry symptoms and those with both elated and irritable mood.
It is also possible that one of our questions on the RBC transfusion trigger might have prompted reports of a more restrictive transfusion trigger because we, the survey investigators, had conducted the only major randomized trial in this field.
An analytical review methodology was selected as preliminary research suggested that much of the literature was in the form of quite descriptive evaluation and policy reports which a more restrictive systematic review methodology may exclude.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com