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More restrictive filtering such as the Seven Golden Rules [20] (orange) further reduce the number of molecular formulas to be considered; nevertheless, multiple explanations remain for most precursor ions.
Similar results were obtained we used the more restrictive filtering criteria (Fig. 2C F and Table S2C,D).
When oscillatory potentials informative of the third-order neurones, namely amacrine cells, were isolated with a more restrictive filtering of the ERG recordings, no significant difference could be detected (Fig. 3d, e).
If the number of replicates is low it might be necessary to set more restrictive filtering limits to ensure that the comparisons between experimental conditions are done with a minimal amount of reliable information.
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It is understood that by applying more restrictive filters, we may filter out the correct molecular formula, limiting novel discoveries; this is particularly the case if we restrict ourselves to molecular formulas from some molecular structure database such as PubChem.
Alternatively, these problems may be addressed by less costly methods on a typical widefield fluorescent microscope with minimal expression times, more restrictive bandpass filter technology, and the use of multiple fluorescent proteins that are more spectrally distinct from each other.
Internet filters at the least restrictive setting block about as much pornography as filters at more restrictive settings, but the number of blocked health sites jump, researchers said: half the Web sites devoted to safe sex and similar topics are stopped at the most restrictive settings, which are used at many schools and libraries.
However, those filters represent more restrictive design constraints for human DNA with only 24% of the 50-mer oligonucleotides on the array being accepted compare to 35% in the C. elegans case.
For example, when I set the filters to be more restrictive, they blocked not only all inappropriate sites but also sites like Amazon.com and CNN.com.
If too many retrievals are obtained, more restrictive searches (contingency searches) are conducted by activating additional filters.
Because the similarities between the DR and Rapa groups might be masked by the filtering criteria we employed, we used a more restrictive criteria: > 30% change with q < 0.05 and > 15% with q < 0.001.
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