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This mechanism occurs due to the development of a more resistant state in most bacterial cells.
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The lower insulin-stimulated glucose uptake together with the significantly higher insulin:glucose ratio in the LRS group suggests these animals are moving towards a more insulin resistant state.
Simulation studies demonstrate the usefulness of rearing animals more resistant to carrier state in the prevention of disease propagation in poultry, in synergy with vaccination [ 3].
This stress response could be considered a form of 'hormesis' in which a sub-lethal 'dose' of infection could temporarily promote a more stress-resistant state.
This suggests that increased hepatic miR-34a expression, which may be found in carriers of the rare allele of rs72631823, could promote a more insulin-resistant state and compound the deleterious effects on islet function of higher miR-34a expression.
Yes, I do think those were halcyon days even though the struggles were hard and the state more resistant to change.
Selection and breeding of chickens more resistant to Salmonella carrier state, i.e. able to rapidly clear Salmonella, could reduce the spread of these bacteria in poultry stocks and hence improve food safety.
If the ancestral state of pre-eukaryotic sex resembled the conjugational process observed in H. volcanii, it is conceivable that cell-cell fusions allowed the formation of diploid/polyploid states more resistant to deleterious mutations.
The up-regulation of the pmr operon in swarm cells suggests that cells in the swarm state should be more resistant to polymyxin than those in the vegetative state.
Carriers of the ER22/23EK polymorphism showed significantly more joint erosion and were treated more frequently with anti-TNF α therapy, which suggests that a relative GC resistant state is related to a more severe disease phenotype.
However, once W settled in the high state, it was more resistant to inactivity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com