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Two scenarios are combined to a new more relevant scenario.
This proteolysis mechanism would likely also apply to VEGF bound to cell-surface HSPGs, which is a more relevant scenario for a tip cell lacking a basement membrane.
However, from a patient's perspective, stochastic loading may be a much more relevant scenario, since it mimics the random, physiological motions experienced in daily activities.
However, they validated their method in a more relevant scenario, showing that when the method is used to select decoys generated by ROSETTA (Das and Baker, 2008), there is a statistically significant enrichment in correct models.
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Finally, they tested the role of the peroxynitrite-PARP-dependent pathway in animals challenged with high tidal volume only, thus leaving its role in clinically more relevant scenarios open to speculation.
Second, more environmentally relevant scenario, agglomeration may be accepted and dose derived from nominal concentrations.
To represent a more clinically relevant scenario, we subsequently injected MB49 tumors to establish the tumor, then after 8 days we labeled in vivo via intravesicular instillation of colloidal PEG Gd2O3 TRITC MSN particles (1 mg MSN in 50 μL PBS).
In the present work, we sought to validate the use of VEGF-A, sFlt-1, Ang-1 and Ang-2 levels as biomarkers of septic shock development in a larger and independent cohort of patients with cancer-associated FN, in a more clinically relevant scenario regarding the use of a sepsis biomarker.
Our study comparison groups were also different, as we used a more clinically relevant scenario, looking for clinical differences between workers with definite MWF-HP, and workers without definite MWF-HP (many having occupational asthma or humidifier fever), within a group who had all previously been suspected of having HP during an outbreak investigation.
To better understand the role of CBH I-water interactions in the presence of PEG in more relevant industrial scenarios, we used a commercial cellulase mix, Cellic CTec2.
As such we have a viable mathematically tractable model of a noisy neural tissue that would be of interest to explore in a variety of more neurobiologically relevant scenarios.
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more relevant developments
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com