Hence, although the CSF may be a more relevant compartment, assessment of biochemical neuro-markers in cardiac arrest patients is better performed in blood.
Studies of animals performed nearer to the time of slaughter are likely more relevant for assessment of the potential for foodborne exposure, yet limited epidemiological investigations have been performed in feedlot cattle [ 11, 20].
Thus, to make our simulation comparison more relevant, our assessment of hypothesis testing methods and RAR procedures is based on the calculation of both statistical power and the comparison to the nominal type I error rate.
These data suggest that combined analysis of tumour Ki67 and sCAIX expression may provide a more clinically relevant assessment of tumour hypoxia in OSCC.
To provide a more clinically relevant assessment of MEDI-565 activity, we used the short-term cultured human metastatic colorectal cancer cells derived from surgical resections of patients previously treated with oxaliplatin and fluorouracil-containing regimens.
Although the DAS28 has been validated in patients with RA, 26 it has not been validated in patients with UA, so swollen and tender joint counts may be a more clinically relevant assessment in these patients; the proportion of patients with zero swollen and tender joints was fivefold greater in the abatacept versus placebo groups at month 6.
These new testing approaches will involve complex end points such as signature profiles and biomarkers of in vitro pathway perturbations, more relevant exposure assessments, population-based studies with molecular and genetic components, and the use of predictive toxicity algorithms based on computational systems modeling.
The same may apply to quality-of-life assessment, a problem in almost all centres, although this is more relevant to outcome assessment during follow up than to the formulation of treatment plans at time of presentation.
We emphasize the need for a coherent definition of recovery for more relevant ecosystem risk assessment and management.
Migration data are considered more relevant for risk assessment than content data, since it is only the fraction of a substance leaching or migrating from the rubber granulate that football players can actually be exposed to.
