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As a consequence, the condensed chromatin is transformed into a more relaxed structure that is associated with greater levels of gene transcription; however, this relaxation can be reversed by HDAC activity [ 7].
Alternatively, SP I expressed in insect cells may assume a more relaxed structure, allowing binding of guanine nucleotides.
H2A may contribute to a more relaxed structure of the host genome, thus facilitating the inserting of T-DNA.
Acetylation of histone releases condensed chromatin into a more relaxed structure that is associated with greater levels of gene transcription.
The superhelical turns of the DNA do not remain constant throughout the nucleosome, with a more relaxed structure observed towards the outer regions than at the central dyad [23].
Similar(53)
However, an attractive model proposes that HDACi affect transcription by promoting acetylation of histones – resulting in a more relaxed chromatin structure in part by chromatin remodelling and by changes in the structure of proteins in transcription factor complexes (Xu et al, 2007).
For example, the P1-mm-H allele with dark mosaic pigmentation would be expected to have a more relaxed chromatin structure than the P1-mm-L allele that produces light mosaic pigmentation.
Capuchin monkeys exhibit a more relaxed social structure than other monkey species, such as Japanese macaques [10], [38], yet the order of acquisition of techniques suggests that rank played a strong role in the transmission process and in opportunities for learning.
In general, HDAC inhibition promotes a more relaxed chromatin structure, allowing transcriptional activation.
To test if enhanced formation of BPDE DNA adducts was due to a more relaxed chromatin structure, we examined chromatin accessibility in GM04312C cells after iAsIII treatment.
In general, a more relaxed matrix variable structure is derived based on improved scalar parameter approach from the perspective of eigenvalue theory, which is then applied to obtain less conservative filter design condition with linearized matrix variable inequality in the first stage of provided algorithm.
Related(20)
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