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A/A genotype was associated with a more reduced expression of sCTLA-4 protein in patients than in the controls (1.76 ± 0.19 versus 1.91 ± 0.30, resp; P < 0.0007).
Taken together, these results show a sex-specific remodelling of MLCL species with longer acyl chains in females and a more reduced expression of enzymes involved in fatty acid synthesis pathway in doxorubicin-treated males than females (Additional file 1: Figure S3).
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However, we observed more differentiation and reduced expression of pluripotency genes when FGF and Activin A were removed together.
Strikingly, 5 of the 7 genes that had more than 4-fold reduced expression in antibiotic treated mice encode known antimicrobial factors[24] [29] (Table 1).
Thus, we predicted that late replicated chromosome regions will tend to evolve more rapidly because of relatively reduced expression and hence weaker purifying selection for translational efficiency.
Our observed 3.70 fold down-regulation of SCN1B in the poor-responders indicates that the tumor environment may become more pro-migratory due to reduced expression of this factor.
Amphiregulin expression was more reduced in group 3 (low PEEP (1 cmH2O), low VT (7 mL/kg) without RMs) compared to other groups.
The second main reply to the surface form argument is that surface form may be a reduced expression of a more complex logical form.
More genes showed increased expression over reduced expression (55 vs 45%).
Dmeglob3 mRNA expression was even more reduced (to 23% after 1% O2 for 3 h; Figure 5D).
The data suggest that decreased ALCAM expression is of clinical significance in breast cancer, and that reduced expression indicates a more aggressive phenotype and poor prognosis.
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