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Recent genetic engineering and more recently genomic approaches have significantly boosted our understanding of the regulation of amino acid metabolism in plants and their participation in growth, stress response, and reproduction.
More recently, genomic tests to determine which, if any, molecules are expressed by the cancer cells have been used to subcategorize breast cancers and guide treatment decisions.
More recently, genomic studies have opened the door to studying genetic differences between populations, bringing us the possibility of more effective individualized medicine.
More recently, genomic technologies have provided high-throughput integrated approaches [15] to investigate global gene expression responses not only to drought but also to other abiotic stresses [9].
More recently, genomic sequencing of Bacillus thuringiensis (Bt) isolate IBL 200 from the Invasive Insect Biocontrol and Behavior Laboratory (IIBBL; Beltsville, MD, USA) collection revealed the presence of an apparent toxin-encoding operon similar to tca of P. luminescens W14 [1], and reports of similar tca genes in a Paenibacillus sp. and in Bt have appeared in the patent literature [5], [6].
More recently, genomic studies have sought to identify possible physiologic pathways to explain the symptoms experienced by patients with fibromyalgia.
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In support of BRCA1 methylation conferring an HR defect, it has been associated with the same gene expression signature and copy number alterations observed in BRCA1-mutated HGSOC25 and, more recently, with genomic signatures suggesting HR deficiency in breast cancer26.
More recently, similar genomic response was observed in lung fibroblasts [ 14].
More recently, rice genomic DNA was hybridized to an oligonucleotide microarray to detect SFPs [ 6] with an up to 20% false discovery rate.
More recently, comparative genomic hybridisation analysis identified a frequent loss of PTCH1 locus and amplification of GLI1, independently of the breast tumour subtype [ 53, 54].
Thereafter, 700 new Gh-prefixed SSRs [ 24], new NAU-prefixed SSRs [ 7, 25], and more recently 2937 genomic SSRs (gSSRs) (Monsanto Company) [ 26] have been released.
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