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More recently, genetically modified common marmosets have been produced successfully and their transgenes have been transmitted through the germ line.
More recently, genetically engineered mouse (GEM) models have been developed that might more closely mimic the human disease at the molecular level.
More recently, genetically matched human iPSC clones from dermal fibroblasts and bone marrow stromal cells of the same donor were generated and differentiated into osteogenic and chondrogenic lineages.
85 More recently, genetically engineered T cells which express chimeric immune receptors have been shown to specifically lyse EGFRvIII-expressing gliomas cells in in vitro and in vivo studies.
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More recently, genetically-engineered variants of GFP that report neuronal activity have been developed, notably calcium sensors such as GCaMP [13] and the pH-sensors such as pHluorins [14], but even the best of these indicators have yet to reach the resolution necessary to detect single spikes in single neurons [15] and their use in vivo is limited.
More recently, he genetically modified Cavendish banana plant lines by inserting copies of the most promising of these two genes – called RGA2, then planted them at a site heavily infested with TR4 in Australia.
More recently, a genetically encoded FRET-based Pb2+ sensor, Met-lead 1.59, was developed for cellular detection (Table 10).
In this respect, it is of note that better protection appears to be obtained against challenge viruses that were isolated in the 1930s and 1970s (i.e. Herts33/56 and California71), and which are genetically more closely related to current vaccine strains than the more recently isolated and genetically more distinct Netherlands/93 virus (Lomniczi et al., 1998).
These feedstocks include non-edible oils such as Jatropha curcas and Calophyllum inophyllum, and more recently microalgae and genetically engineered plants such as poplar and switchgrass have emerged to be very promising feedstocks for biodiesel production.
More recently, new and genetically distant viral strains have been detected in rats [ 8], ferrets [ 9], foxes [ 10] and bats [ 11], but the current HEV classification has not been modified yet.
More recently, rice varieties were genetically improved by the altered expression of various nitrate transporter genes8,9, pointing to the uptake of nitrate as crucial factor for the NUE in these varieties.
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