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JUST as the introduction of the printing press in Europe in the late 15th century led many scribes of the time into a state of unemployed despair, so the more recent spread of the computer whose typefaces can reproduce calligraphic designs of enormous variety has made many latter-day scribes redundant.
They suspect that it was responsible for the sudden spread of the Indo-European group of humanity about 4,000 years ago, and also for the more recent spread of the Tutsis in Africa, whose ancestors independently evolved a tolerant version of the gene.The pressures behind other changes are less obvious.
However, the emergence of cryptococcosis due to an uncommon molecular type of C. gattii (VGII) in humans and animals on Vancouver Island, BC, Canada, and its more recent spread to mainland British Columbia and the adjacent Pacific Northwest of the United States has changed this paradigm [4], [5], [6], [7], [8], [9].
Given the usual geographic separation of B. pseudomallei STs, we suggest that this wide-ranging presence of ST562 might result from more recent spread caused by transmission between regions.
In the early 2000s most HIV infections in Accra originated from contact with sex workers (Cote et al. 2004), with more recent spread from these core risk groups to the general population.
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More recent local spread of lineages U6b and U6c also parallel the M1b and M1c1 distributions.
Site-based programs in the workplace were initiated in 1999; the other four more recent publications were spread from 2008 to 2010.
Combined data for the Netherlands and Vietnam showed significantly more atypical Beijing isolates among patients >75 years of age (odds ratio [OR] 2.96, 95% confidence interval [CI] 1.15 7.67) (Table 1), which suggests more recent introduction and spread of typical Beijing strains.
On the other hand, low intra-lineage variability of DOBV-Af and DOBV-Ap strains indicates more recent and rapid spread of these viruses in yellow-necked mouse and Black Sea field mouse populations.
The Spanish flu "claimed at least 20 million people," Issa said, noting that more recent outbreaks of easily spread flu in the 1950s and '60s killed tens of thousands of people.
In more recent decades, it has spread to many other parts of the world, including East Africa, the Middle East, and Asia.
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