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Exact(8)

Hence, populations with shorter LDU maps have been founded more recently, experienced a more recent selective sweep, or have a smaller effective population size (such as some population isolates) compared to those with longer maps (such as Sub-Saharan African populations).

In some cases, these tests also take into account data concerning polymorphism within species, making it possible to detect both older and more recent selective events.

Our genome-wide scan for anomalous SFS confirms that the X chromosome of D. mauritiana has experienced more recent selective sweeps than have the autosomes.

More recent selective IRAK4 inhibitors have utilised high-energy hydration sites to design three selective nanomolar IRAK4 ligands (Supplementary Table 1) (Robinson et al, 2010).

To gain insight into the more recent selective events in Primates, we applied a population genetics phylogenetics approach to study the evolution of OAS genes, MB21D1, TMEM173, and RNASEL in the human, chimpanzee, and gorilla lineages.

An alternative possibility is that, as in the case of the gene regions that we described as neutrally evolving, weaker and more recent selective events have been maintaining the opposite risk alleles.

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Similar(52)

It may be noted that the volume fraction values are close to those reported with more recent ion-selective microelectrode measurements that will be described below.

Few of these analogs for instance, compounds 6, 7 and 8 are shown to be more effective than recent Selective Estrogen Receptor Modulators (SERMs) i.e. Ospemifene and Tamoxifen, against these cell lines.

Dualsteric/bitopic hybrid compounds which consist of at least two pharmacophores combined in one single ligand are more recent examples for functionally selective ligands.

More recent pharmacological molecules include selective ER down-regulators (SEDRs), which inhibit ERα dimerization and nuclear translocation or aromatase inhibitors, which target the enzyme responsible for estrogen synthesis.

More recent approaches have included selective insertional gene trapping or FACS sorting of cell lineages labelled with GFP in e.g. zebrafish followed by gene chip analysis.

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