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Historical specimens, when available, can provide new insight into the distribution and evolution of pathogens that may not be discernible from more recent samples.
This revealed that the Dd2-type deletion allele had a high frequency (72%, the major allele within 44 of 61 clinical infection samples genotyped), similar to that in the more recent samples from the same area.
Deposits were dated to between 35,000 and 700 years BP. 13C isotopic data revealed a trend toward enriched values in older samples (− 14.21‰) in which C4 plants dominated and a relative impoverishment of the values in more recent samples (− 26.9‰ to − 27.9‰).
Focusing on more recent samples, these differences appear to be fairly constant.
Specifically, NuDNA was successfully extracted and sequenced from 11/14 samples, the exceptions being the oldest sample, collected 94 years ago, and two more recent samples (Table 1).
Using stored sputum smears, and more recent samples, we now characterise the strains present in the population over a 20 year period from 1986, examining trends and patient characteristics over time.
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With advances in device engineering and increased experience of physicians, we hypothesized that the rates of these complications would be reduced in a more recent sample set.
Studies with more recent sample periods mainly focus on the unconditional lagged relation.
None of the GPs from the first cohort were using a computer, while all of the GPs our more recent sample did.
Interestingly, the only multiple sample from any of the patients, head and neck samples 11 and 12, are sequential samples of which only the more recent sample showed significant levels of anti-p53 antibodies.
Assessing a more recent sample of studies after the implementation of the CONSORT guidelines may increase the number of low risk studies and may provide a more certain estimate of the impact of risk of bias on effect size.
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more recent papers
more recent samplers
more recent materials
more recent tests
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more recent surveys
more recent lists
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more recent models
more past samples
more up to date samples
more recent hits
more recent polls
more recent immigrants
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more uncleared samples
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