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Taking a wider perspective, we show how the sunspot index stands the test of time versus more recent quantitative indices, but we also consider the prospects and possible options for a future transition from the visual sunspot index heritage towards an equivalent global activity index.
More recent quantitative work using geometric morphometrics techniques [15], [18] may conflate differences in foot anatomy and shape with differences in locomotor biomechanics.
While some studies have reported kni expression in D. melanogaster at C12 (Rothe et al., 1989, 1994), more recent quantitative measurements could not detect kni before the mitotic division preceding the interphase of C13 (Jaeger et al., 2007).
Nevertheless, more recent quantitative kinetic analyses have revealed that some RNA pol I subunits, including RPA39, RPA16 and RPA194, transiently dissociate from the NORs during metaphase and reappear in anaphase (Chen et al. 2005; Leung et al. 2004).
While these data are exploratory and do not incorporate more recent quantitative methods of measuring tumor response, the possibility of using TLE3 as tool to predict response in the neoadjuvant setting is intriguing and warrants further study in a prospective trial [ 15].
The same phenotype has been observed in kni mutants of D. melanogaster (Jäckle et al., 1986; Gaul and Jäckle, 1987; Harding and Levine, 1988; Strunk et al., 2001), although a more recent quantitative study was not able to detect it (Surkova et al., 2013).
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More recent breeding, quantitative genetic, and modeling studies generally found positive contributions of Glu-3 loci to parameters related to dough strength, extensibility and bread-making quality [13], [30], [32] [36], [38], [56], [57].
We concur, and have expanded our introduction to highlight more recent successes in quantitative immunology.
Although initial studies (for review see [ 14]) were implemented using rather crude stimulating devices, some of the more recent methodologies allowed quantitative evaluation of this sensory modality [ 14, 15, 20, 21].
More recent experiments have shown quantitative matches to the predictions of these models [16] [22].
A more recent study using a quantitative fluorescence assay analyzed 2 cohorts (n=340 and 204) of stage I to IV NSCLC in FFPE tissue microarrays.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com