In more recent studies, the mutant eIF4ES209A mouse was also shown to be resistant to polyoma middle-T driven mammary tumours [ 65].
In a more recent study, a mutant Cpa strain was shown to produce up to 17.8 g/L butanol from pure glycerol at very high rates from high-density cultures, with minimal byproduct formation [ 9].
More recent reports suggest that mutant p53 can interact with p73 and p63 by an association through the DNA-binding domain of the mutant protein, thus inactivating p73 (and p63) function (Strano et al, 2002; Bensaad et al, 2003).
More recent studies described 2 C3 mutants that bind CFB with higher affinity, resulting in a more stable C3 convertase complex.
These studies include experiments on the reeler mouse mutant, and more recent attempts to manipulate developmental fates by pharmacological interventions and transplantation techniques.
More recent studies examined the ΔGlu22 mutant of Aβ, found in an AD kindred in Osaka, Japan [ 60].
More recent studies indicate that this mutant is also able to recognize more than 10 phenylalanine derivatives with large meta substitutions (Tuley and Liu, unpublished data).
More recent studies indicated that the mutant cells of Aspergillus fumigatus with deletion of the lysF gene, encoding homoaconitase, exhibited attenuated virulence in a lung tissue of mice infected intranasally with A. fumigatus cells (Liebmann et al. 2004).
This variable geographical distribution suggests either different migration patterns or the more recent occurrence of the latter two mutant haplotypes.
A more recent study using an insertional htrA mutant in GAS confirmed the earlier report showing a growth defect at 37°C (Jones et al., 2001; Lyon and Caparon 2004); however, an in-frame htrA mutant in serotype M14 GAS strain HSC5 had no growth defect at 37°C (Lyon and Caparon 2004).
